Dynamics of neuron-induced astrocyte tiling and self-avoidance

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Self-avoidance and tiling: Mechanisms of dendrite and axon spacing.

The spatial pattern of branches within axonal or dendritic arbors and the relative arrangement of neighboring arbors with respect to one another impact a neuron's potential connectivity. Although arbors can adopt diverse branching patterns to suit their functions, evenly spread branches that avoid clumping or overlap are a common feature of many axonal and dendritic arbors. The degree of overla...

متن کامل

Dscam-mediated repulsion controls tiling and self-avoidance.

Recent studies have uncovered the molecular basis of self-avoidance and tiling, two fundamental principles required for the formation of neural circuits. Both of these wiring strategies are established through homophilic repulsion between Dscam proteins expressed on opposing cell surfaces. In Drosophila, Dscam1 mediates self-avoidance, whereas Dscam2 mediates tiling. By contrast, phenotypes in ...

متن کامل

Self-repairing Learning Rule for Spiking Astrocyte-Neuron Networks

In this paper a novel self-repairing learning rule is proposed which is a combination of the spike-timing-dependent plasticity (STDP) and Bienenstock, Cooper, and Munro (BCM) learning rules: in the derivation of this rule account is taken of the coupling of GABA interneurons to the tripartite synapse. The rule modulates the plasticity level by shifting the plasticity window, associated with STD...

متن کامل

Astrocyte-to-neuron conversion induced by spinal cord injury

Spinal cord injury (SCI) triggers pronounced astrocyte reactivity (astrogliosis) including astroglial proliferation and migration toward the injury site participating to the formation of a glial scar. Since the mid-20th century, SCI-induced astrogliosis was mainly regarded as detrimental for successful axonal regeneration. However, more recent studies have shown astrogliosis as a multifactorial...

متن کامل

Endocannabinoids Mediate Neuron-Astrocyte Communication

Cannabinoid receptors play key roles in brain function, and cannabinoid effects in brain physiology and drug-related behavior are thought to be mediated by receptors present in neurons. Neuron-astrocyte communication relies on the expression by astrocytes of neurotransmitter receptors. Yet, the expression of cannabinoid receptors by astrocytes in situ and their involvement in the neuron-astrocy...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Proceedings for Annual Meeting of The Japanese Pharmacological Society

سال: 2020

ISSN: 2435-4953

DOI: 10.1254/jpssuppl.93.0_2-o-032